Progeria ( Hutchison-Gilford Syndrome)

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Just before his passing on January 10, 2014, Sam Berns was a Junior at Foxboro High School in Foxboro, Massachusetts, where he achieved highest honors and was a percussion section leader in the high school marching band. He also achieved the rank of Eagle Scout in the Boy Scouts of America. Sam was diagnosed with Progeria, a rare, rapid aging disease, at the age of 2. He is featured in the Emmy award-winning documentary Life According to Sam, which premiered on HBO on October 21, 2013, 2 days before his 17th birthday. He just turned 17. A few years ago,before his freshman year in High School, he wanted to play snare drumin the Foxboro High School Marching Band, and it was a dreamthat he just had to accomplish. But each snare drum and harness weighed about 40 pounds each, and he have a disease called Progeria . So just to give you an idea,he weigh only about 50 pounds. So, logistically, he really couldn't carrya regular sized snare drum, and because of this the band directorassign...
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VITAMINS AND THEIR IMPORTANCE (PART-I)

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 VITAMINS AND THEIR IMPORTANCE 

(PART-I)


What are vitamins?

There are some nutrients that our body does not make on its own but are required for normal functioning and growth of our body. Thus we must obtain them from the foods we eat,  or via vitamin supplements.
They are essential for providing good health and are necessary for many life functions.
Vitamins are a group of organic compounds that exists in food & functions in a variety of capacities of our body.

Supplements that aid in suppressing  stress
Increasing serotonin levels in the brain wards off stress-related symptoms like depression,  irritability, and frustration.
The mineral magnesium can help to regulate serotonin levels.
Antioxidant supplements can also break up free radicals that cause harm to your body.

TYPES OF VITAMINS?

1-The B Vitamins
B‐1, B‐2, B‐3, B‐6, B‐12
2-fats soluble vitamins.
Here are the water-soluble vitamins which are called the B-vitamins 

B‐1 Thiamin (Vitamin F)
Important in:
  1. Producing energy from carbohydrates
  2. proper nerve function
  3. stabilizing the appetite
  4. promoting growth and good muscle tone
  5. ATP production
Sources of B‐1
  1. Pork
  2. Fish
  3. Liver
  4. Legumes
  5. Nuts
  6. Whole grain or enriched slices of bread and cereals
Warnings: B‐1 is non-toxic even at high dosages
B‐1 Deficiency
  • Loss of appetite
  • Weakness & Feeling tired
  • Insomnia
  • Loss of weight
  • Depression
  • Heart & Gastrointestinal problems
Who’s at Risk?
  • Homeless & Malnourished
  • Alcoholics
  • People with malabsorption conditions
B‐2 Riboflavin
Important in:
  • energy production
  • carbohydrate, fat, and protein metabolism
  • formation of antibodies and red blood cells
  • cell respiration
  • maintenance of good vision, skin, nails, and hair
  • alleviating eye fatigue
Sources of B‐2
Large amounts in
  1. dairy
  2. eggs
  3. meats
Small amounts in
  1. leafy green vegetables
  2. enriched grains
Warnings: B‐2 is nontoxic at supplemental and dietary levels. Light can destroy riboflavin, so purchase milk in opaque containers.

B‐2 Deficiency
  • itching and burning eyes
  • Cracks and sores in mouth and lips
  • Bloodshot eyes
  • Dermatitis
  • Oily skin
  • Digestive disturbances
Who’s at Risk?
  • People with cataracts
  • People with Sickle Cell Anemia
  • Alcoholics
B‐3 Niacinamide & Niacin
Important in:
  • energy production
  • maintenance of skin and tongue
  • improves circulation
  • maintenance of the nervous system
  • the health of the digestive tract
Warnings: In doses of only 50‐100 mg nicotinic acid can cause dilation of blood vessels and potentially painful tingling (“niacin flush”),  diarrhea, nausea, vomiting, and long term liver damage. Nicotinamide is almost always safe to take,  although a few cases of liver damage have been reported in doses of over 1000  mg/day.

B‐3 Deficiency
  • Pellagra: a disease caused by B‐3 deficiency, rare in Western societies
  • gastrointestinal disturbance, loss of appetite
  • headache, insomnia, mental depression
  • fatigue, aches, and pains
  • nervousness, irritability
Who’s at Risk?
Most people get plenty of B‐3 from their diet because it is added to white flour.

B‐6 Pyridoxine
Important in:
  1. Production of red blood cells
  2. conversion of tryptophan to niacin (B‐3)
  3. immunity
  4. nervous system functions
  5. reducing muscle spasms, cramps, and numbness
  6. maintaining a proper balance of sodium and  phosphorous in the body
  • Warnings: High doses of B‐6 may be recommended to treat PMS, carpal tunnel syndrome, and sleep disorders, but continued use of high doses may result in permanent nerve damage.
  • Pregnant women should always consult their doctor before taking this supplement and all others.
B‐6 Deficiency
  • nervousness, insomnia
  • loss of muscle control, muscle weakness
  • arm and leg cramps
  • water retention
  • skin lesions
Who’s at Risk?
  • very rare
  • alcoholics
  • patients with kidney failure
  • women using oral contraceptives
                          B‐12 Cobalamin
Important in:
  1. proper nerve function
  2. production of red blood cells
  3. metabolizing fats and proteins
  4. prevention of anemia
  5. DNA reproduction
  6. energy production?
Warnings: Vegetarians need to look for fortified sources  (soy milk, supplements).The Elderly often have trouble absorbing.

B‐12 Deficiency
  • anemia
  • nerve damage
  • hypersensitive skin
Who’s at Risk?
  • pernicious anemia– B‐12 injections often taken regularly
  • HIV
  • Chronic Fatigue Syndrome
Now its up to you to choose which one
now it's up to you to choose which one

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